Christian Ehrenfried von Weigel (24 May 1748 – 8 August 1831) was a German scientist and, beginning in 1774, a professor of chemistry, pharmacy, botany, and mineralogy at the University of Greifswald.

Born in Stralsund, in 1771 he received his medical doctorate from the University of Göttingen, having studied under Johann Christian Erxleben.

Among other things, Weigel developed a cooling heat exchanger (German Gegenstromkühler) (1771), which was later improved upon by Justus von Liebig and then became known as the Liebig condenser (Liebigkühler).

In 1792, he was elected a foreign member of the Royal Swedish Academy of Sciences.

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