He is the lead guitar player for the hard rock band Stone Sour, Corey Taylor, and former member of Black Star Riders.

[2] He was born in Philadelphia and was a founding member of Thousand Watt Stare, Black President,[3] the Strychnine Babies and the Chelsea Smiles.

[5] In September 2018, it was announced he would replace Damon Johnson as lead guitarist in Black Star Riders[6] from January 2019.

[8][9] In February 2021, Martucci formed the side project Dirty O'Keeffe[10] with Billy Gould (Faith No More), Dave Raun (Lagwagon), and Steven Shepard (Trash N' Privilege).

[11] Martucci uses or has used guitars by a variety of brands including Gibson, Gretsch, Marvin, Zemaitis, Dean, and Charvel.