After graduating from Illinois Wesleyan University School of Theatre Arts, Moore moved to Los Angeles to pursue her acting career.

Her television credits include the UPN comedy The Bad Girl's Guide and the drama Hyperion Bay, recurring roles on Pasadena and Unhappily Ever After, and guest appearances on 24, Just Shoot Me!, Friends, and Suddenly Susan.

[citation needed] Moore joined the cast of MADtv in 2002 as a featured performer for the eighth season, where she was noted for her impressions of Christina Aguilera, Shannon Elizabeth, Sharon Stone, Trista Rehn and Brittany Murphy.

She also narrates various audio books, including Diane Duane's Young Wizards series and Yellow Star.

Moore is a founding member of Bitches Funny, an all-female sketch group that has performed in New York City and Los Angeles for the past five years.[when?]