[2] In 2022, she was appointed to the Order of Ontario for having "opened the ears of music lovers internationally through numerous classical and contemporary performances.... As a Professor of Musicology and Piano at York University, she has received esteemed research awards.

Her double album of the complete Glass Houses cycle by her late friend, composer Ann Southam, "remains Centrediscs' best-selling CD of all time".

[12] As a duo with violinist Jacques Israelievitch, she recorded an album of Canadian music on Centrediscs and the Mozart violin and piano sonatas on the Fleur de Son label.

[14] In 2006, on board the Space Shuttle Atlantis, MacLean took the recording of her as soloist in the world premiere performance of David Mott's piano concerto Eclipse.

Following his death in 2000,[24] in his memory she created The Christina and Louis Quilico Award,[25] which is administered by the Ontario Arts Foundation and held every two years under the auspices of the Canadian Opera Company.