Christine Holt

[6][7] In 1986, she became an assistant research biologist and lecturer at UCSD, where she continued to study the frog visual system in its early embryonic period.

In 2017, Professor Holt was awarded the Ferrier Medal and Lecture by the Royal Society "for pioneering understanding of the key molecular mechanisms involved in nerve growth, guidance and targeting which has revolutionised our knowledge of growing axon tip.

[14] Holt's early career was spent studying cell movement during eye development in the frog visual system.

[15] Much of what we currently know about the cellular and molecular mechanisms involved in establishing and sculpting the patterns of retinal projections comes from the work of Holt and her colleagues.

[16] Today, her research interests continue to lie in the mechanisms of axon guidance[7] and synaptic specificity in the development of complex brain networks.

[1] Holt is credited as the pioneer of the idea that proteins synthesize and degenerate at a local level in an axon's cone of growth.

[20] Currently, Holt collaborates with the lab of Giovanni Armenise at Harvard University, focusing on the role of microRNAs and non-coding RNAs in axon regrowth and wiring, and as a possible link to cancer of the nervous system.