She sang songs such as "The Blue Danube" and "Voices of Spring" in a Vienna-themed short Soundies musical film, and her performance was singled out as the best of the inaugural series.

At Columbia, she appeared in many short subjects starring Shemp Howard, Harry Langdon, Andy Clyde, Joe Besser, Bert Wheeler, and Hugh Herbert.

Her debut appearance with the Three Stooges was in Idle Roomers, followed by a solo Shemp Howard short, Open Season for Saps.

McIntyre's singing voice was featured prominently in 1945's Micro-Phonies, as she sang both "Voices of Spring" and "Lucia Sextet" and was also featured in 1947’s Out West (made after Shemp Howard replaced his ailing brother, Curly Howard, in the act) and its 1954 remake Pals and Gals.

Her performance as Miss Hopkins in Brideless Groom featured an acclaimed knockabout scene in which she repels suitor Shemp Howard—right through a door.

Director Edward Bernds remembers: In the story, Shemp had a few hours in which to get married if he wanted to inherit his uncle's fortune.

By this time, McCollum and Bernds had left Columbia, leaving Jules White in charge of short subjects.

White favored strenuous, extremely physical humor, and forced the ladylike McIntyre to submit to low comedy; in a single film, her character was tackled, hit with messy projectiles, covered with cake batter, and knocked into a cross-eyed stupor.

When her contract at Columbia expired in 1954, she was all too happy to retire from show business, eventually developing a career in real estate.