His mother, Frede (Friederike) Marie (1660 –1729, Danzig), was the daughter of his uncle, Christian Albert, Burgrave and Count of Dohna.

Christoph II married in Wildenfels on 18 October 1734 to Gräfin Friederike zu Solms-Wildenfels (28 Mai 1714 – 9 April 1755).

[5] Promotions[6] Christoph II entered Prussian military in service during the reign of Frederick William I of Prussia and initially served in Infantry Regiment Nr.

[8] By the end of 1740, with the death of Charles VI, Holy Roman Emperor, Prussia and Austria were at war over Maria Theresa's succession and inheritance.

[6] After a brief interval of peace, in April 1758 he received the command of Prussia's troops in the Pomeranian Theater, fighting against the Swedes at Stralsund.

Sweden's ally, Russia, sent an army to relieve the blockade, which Dohna held at bay with his small force until the Frederick's arrival with the main army at the Oder; Christoph II subsequently commanded a wing—22,000 strong—of the Prussian force at the first meeting at the Zorndorf, an arguably strategic victory for the Prussians but one at which they suffered high losses.

[7] In the years 1758–1759, campaigning in two theaters, Saxony and Upper Pomerania, some 340 kilometres (210 mi) distant from one another, damaged his health.

Carl Heinrich von Wedel, his successor at Züllichau, engaged the Russian army at the Battle of Kay, which the Prussians lost with high casualties.

[7] After his recall, Dohna lived in Berlin until his death on 19 May 1762; his name is engraved on the Frederick II the Great Equestrian Memorial.