[18] Bosh began garnering significant attention from college recruiters after leading Lincoln High School in Dallas to the top ranking in the country and to the USA Today National Championship with a perfect 40–0 season.

[19] Bosh eventually chose to follow the footsteps of his cousin and aunt and attended Georgia Tech to study graphic design and computer imaging, and subsequently, management.

[21] However, prior to his signing, other NBA teams made offers for Bosh as they knew Toronto needed a veteran scorer, and Raptors star Vince Carter himself pressed for a trade.

[22] Bosh—who cited teammate Michael Curry as his mentor[17]—was often praised by his coaches for his heart, and willingness to play through pain and injuries resulting from his lack of body strength compared to some of the league's strong forwards and centers.

Bosh continued to work on his game as he consistently chalked up double-doubles, leading the team in scoring, rebounding, and field goal percentage for the first half of the season.

[28] On February 9, 2006, for the first time in his career, Bosh was selected to play in the 2006 NBA All-Star Game in Houston, Texas as a reserve forward for the Eastern Conference.

[31] Despite a major off-season revamp of the Raptors roster—including the departure of good friends Mike James and Charlie Villanueva—Bosh officially signed a three-year contract extension with a player option for a fourth year on July 14, 2006.

[49] Before the 2007–08 season began, Andrea Bargnani, the number one pick in the 2006 NBA draft, was slated to start at center and Bosh at power forward to form a strong Toronto frontcourt and Jason Kapono, a three-point specialist, was acquired via free agency from the Miami Heat to add offensive firepower.

[55] General Manager Bryan Colangelo said at a press conference after the series, "Whether it's protecting [Bosh] inside the paint, getting a little bit more of a presence in there, to just getting him another scorer that's going to shoulder some of that burden, it's something that's clear we have to get better", hinting that the roster was in need of an overhaul.

[57] To provide Bosh with an experienced frontcourt partner, the Raptors pulled a blockbuster trade prior to the 2008–09 campaign: six-time All-Star Jermaine O'Neal was acquired from the Indiana Pacers.

Two weeks later, in a bid to bring in a wing player and create greater salary flexibility, O'Neal and Jamario Moon were traded to Miami for Shawn Marion and Marcus Banks.

[68] Following the failure of the 2008–09 campaign, Colangelo knew that he had to shake up the roster to persuade Bosh to stay, and the Raptors were one of the busiest teams in the pre-season market.

On April 5, 2010, he was named the Eastern Conference Player of the Week, winning the honor for the seventh time in his career (tying Carter for the most in franchise history).

Bosh was active on the social media front, posting his thoughts on Twitter and having a documentary crew record his meetings with the teams interested in signing him.

Bosh signed a 6-year, $110 million contract with the Miami Heat on July 10, 2010, through a sign-and-trade deal, which sent two 2011 first-round draft picks to the Raptors (Norris Cole and Jonas Valančiūnas were later selected).

I've loved every minute here and I just wanted to thank you from the bottom of my heart..."[82] Not only did Bosh leave Toronto as its all-time leader in virtually all major statistical categories, he was one of only three players in the league who accrued 10,000 points, 4,500 rebounds, and 600 blocks in his seven seasons with the Raptors.

However, the Heat managed to go on to compile a 21–1 record and were jostling with the Boston Celtics and Chicago Bulls for pole position in the Eastern Conference as mid-season approached.

On January 5, 2012, Bosh led the Heat to a 116–109 triple-overtime win against the Atlanta Hawks, highlighted by a three-point shot he made to force the game into overtime with 0.6 seconds left to play in the fourth quarter.

Bosh averaged 12.1 points per game throughout the playoffs, as the Heat advanced to the NBA Finals to face the San Antonio Spurs following a grueling seven-game series against Indiana.

In the final seconds of Game 6, James missed a three-pointer, and Bosh grabbed the offensive rebound and found a wide-open Ray Allen in the corner.

On July 30, 2014, after wide speculation that he would join the Houston Rockets, Bosh re-signed with the Heat to a five-year, $118 million contract after LeBron James announced that he was leaving Miami to return to the Cleveland Cavaliers.

He faced increasing pressure from physicians and the Heat organization to sit out the rest of the season because of the potential dangers of the recurring medical condition.

[108] On June 2, 2017, the NBA ruled that Bosh's blood clotting issues were a career-ending illness, meaning the Heat would be allowed to remove his contract from their salary cap once they officially released him.

[109] Following Bosh's release, Heat President Pat Riley said, "The number '1' will never be worn by another player and we can't wait to someday hang his jersey in the rafters.

[115] Together with fellow 2003 draftees Dwyane Wade, LeBron James, Carmelo Anthony, and Kirk Hinrich, this team competed in the 2006 FIBA World Championship.

[118] During the tournament itself, Bosh operated as the main backup to center Dwight Howard as Team USA went unbeaten in all eight games en route to the gold medal, defeating Spain in the final.

[124] Indiana Pacers coach Jim O'Brien once commented on the match-up problems Bosh posed for opposing defenders: "We've tried over the years to put big guys on him.

When he was the leader of the Raptors, Bosh was not known for being vocal on the court, preferring to maintain his quiet and humble demeanor but expecting his teammates to match his work ethic.

In 2017, alongside record producer, songwriter, and singer Rico Love, Bosh co-produced a song titled "Miss My Woe" by Gucci Mane.

[148][149][150] On March 24, 2009, it was reported that Bosh's former girlfriend, Allison Mathis, was seeking child support and sole custody of their daughter, Trinity (born November 2, 2008).