The series Star Trek: Strange New Worlds (2022–present), a spinoff of Discovery, is centered on Pike's time as captain of the USS Enterprise, with Mount reprising the role.

At the beginning of "The Cage", set in the year 2254, Pike and his crew are recuperating from a mission to Rigel VII during which several members of the landing party were killed by the inhabitants.

Meanwhile, the Enterprise is en route to Vega Colony to drop off wounded crew members when it receives a distress call from the survey vessel SS Columbia, lost eighteen years previously.

Pike soon learns that all but one of the survivors are illusions created by the Talosians in order to lure the Enterprise crew to Talos IV.

The Talosians make every effort to provide fantasies that they hope will appeal to Pike, using Vina, the only real Columbia survivor, as the object of desire.

At the two-part episode's conclusion, it is revealed that the entire procedure was a Talosian-generated illusion to ensure that the Enterprise reached Talos.

The Talosians invite Captain Pike to spend the remainder of his life among them, "unfettered by his natural body", which was the entire purpose of Spock's actions.

The Talosians then show Captain Kirk an image of Pike in perfect health and reunited with Vina (another scene from "The Cage").

[7] Captain Christopher Pike was introduced to Star Trek: Discovery in the second-season premiere, "Brother", which first aired in the U.S. on January 17, 2019.

Set in the years 2257–2258, the season-long story arc involves Pike assuming temporary command of the USS Discovery while the Enterprise is disabled, in order to investigate the mysterious "red signals" – temporal anomalies appearing throughout space that have some connection to the apparent breakdown and disappearance of Spock.

The planet Talos IV reappears in the episode "If Memory Serves", which also has Pike and Vina once again making mental contact.

He is forced to choose between taking a time crystal from Boreth which would solve the red signal crisis at the cost of his disability in the future or risking the fate of the galaxy.

After Anson Mount left Discovery following the second-season finale, fans of the series began calling for him to reprise his role of Christopher Pike in a spin-off set on the USS Enterprise, alongside Rebecca Romijn as Number One and Ethan Peck as Spock.

In the film, Pike encourages a young, directionless James T. Kirk (Chris Pine) to follow in the footsteps of his hero father and enlist in Starfleet.

In the culmination of the Battle of Vulcan, Pike follows an ultimatum of Nero (Eric Bana) to board the enemy ship.

Pike's death incites a desire for revenge in Kirk, who seeks to hunt down Harrison, nearly bringing the Federation into a full-scale war with the Klingons.

At the end of the film, a memorial service is held for Pike and all of the other people who died as a result of Admiral Marcus and Harrison's actions.

Pike appears in the Pocket Books novels Enterprise: The First Adventure (Vonda N. McIntyre, 1986), Final Frontier (Diane Carey, 1988), Vulcan's Glory (D. C. Fontana, 1989), The Rift (Peter David, 1991), Burning Dreams (Margaret Wander Bonanno, 2006) and Child of Two Worlds (Greg Cox, 2015).

[5]) He also appears in the novel Dark Victory (William Shatner, 1999), and the short story "The Greater Good" (Margaret Wander Bonanno) in the anthology Star Trek: Mirror Universe: Shards and Shadows (2009).

Although extremely popular, the comic series ended on a cliffhanger when Marvel lost the Star Trek license rights.

The crew quickly free the Talosians, who mentally imprison the Klingons in illusions of peaceful, tranquil settings as they purge their memories of Talos IV.

Pike attempts it, in spite of what future-Kirk and future-Spock say, causing him to be injured by the delta rays and subsequently transition to a life in the wheelchair and its light communication device.