Chuprene Municipality (Bulgarian: Община Чупрене) is a frontier municipality (obshtina) in Vidin Province, Northwestern Bulgaria, located in the vicinity of the western parts of Stara Planina range in the so-called Fore-Balkan area.

The area embraces a territory of 330 km2 (130 sq mi) with a population of 2,285 inhabitants, as of December 2009.

[1] Midzhur peak, 2,168 m (7,113 ft), the highest point of the western Balkan Mountains, is located in the municipality almost on the very border with Serbia.

Chuprene Municipality includes the following 9 places all of them villages: The following table shows the change of the population during the last four decades.

According to the latest Bulgarian census of 2011, the religious composition, among those who answered the optional question on religious identification, was the following: An overwhelming majority of the population of Chuprene Municipality identify themselves as Christians.