[5] The church dates back to the 13th Century and was originally constructed from red sandstone hewn blocks.

[7][8] Several of the Osborn crests and mottoes adorn the church which in Latin is 'Quantum in Rebus Inane,' and translates as 'What vanity in human affairs.

[19] The Campton-Cum-Shefford parish registers are notable for events in the 18th century including two people who were ex-communicated for fornication.

[27][28] The church has many notable features; two piscinas (one by the altar and one in the south chapel), alcoves for effigy display[10] and plaques and markers detailing remembrances for the dead.

The window at the south wall of the chancel depicts the Christian virtues Faith, Hope and Charity.

The glass lights, designed by Heaton, Butler and Bayne were made by the Chance Brothers of Oldbury and were dedicated in 1912.

The west end of the church is dominated by the gallery, which was designed and constructed by Peter Farmer in 2002.

Beneath this is the Fred Oakley Room, a Campton resident and benefactor of the church who died in 2000.

The Gothic-style lectern is late 19th century while the pulpit is constructed from parts of a 14th-century screen which includes a traceried panel.

The screen dated back to 1670, but was destroyed in a fire in May 1960 when a sulphur candle used to remove bees in the church had been left unattended.

Amongst those commemorated are Sir Peter Osborn (died 1653), who was Governor of Guernsey when its castle was besieged by the Puritan navy; and John Osborn who, after a distinguished diplomatic career died at Rudolstadt in Saxony in 1814 on the eve of his return to England after eight years as a captive under Napoleon Bonaparte.

The Welsh stone memorial to the pastoral poet Robert Bloomfield was installed in 2003; he is buried in the churchyard.