The Church consists of 124 congregations and 1,298 prayer houses and serves 800,000 members.

[citation needed] The churches meet every two years in a synod.

They have adopted the Belgic Confession, Heidelberg Catechism and Canons of Dort as their doctrinal standards.

Nkhoma Synod HIV/AIDS Community Program was established in January 2000 in response to the growing HIV/AIDS epidemic.

The Reformed Church in America established partner relations with the Nkhoma Synod.