The church was built from 1723 till 1732, when it was blessed by Marko Dragojević.

It was built by Franciscan monks who moved to Vukovar from the village of Srijemske Laze.

In 1991, during the battle of Vukovar, in the Croatian War of Independence, the church was extensively damaged.

In 1995, during the Serbian occupation of city, body of Saint Bono was burned.

After reintegration of Vukovar, in 2000 on church and monastery was installed a new roof.