St. Vitus's Church Complex was a former late-nineteenth-century Roman Catholic church located in Pilsen, Chicago, Illinois, at 1814 South Paulina Street, and corner of 18th Street.

The National Trust for Historic Preservation profiled the structure as a good example of adaptive reuse: "A community task force collaborated with area interfaith organizations to develop a non-profit community development corporation called The Resurrection Project.

The church was renovated 1992–1996 as a "state-of-the-art day care facility was designed for the former parochial school, and plans are underway for a cultural center in the now hollow sanctuary space that was destroyed by a fire….The Resurrection Project operates one of the most active community reinvestment programs in the area from the [church]," costing $1.2 million for conversion of school and $400,000, anticipated repairs to church.

[1] Its location in a Latino neighborhood enabled its large number of parishioners to work with the Roman Catholic Archdiocese of Chicago to explore reuse options with a team of architects, urban planners, historic preservationists, low-income housing specialists, commercial developers, and educators to create Guadalupano Family Center, a day care and cultural activity center.

[2] Opened in 1994, the child care facility "that operates on a sliding scale fee, serving the population of 6,000 children between 3 and 12 years of age living within 1/2 mile of the center.