Sacra Famiglia ("Holy Family", called also chiesa di San Giuseppe or Mezzana or Culliggeddu because of its small dimensions) is a religious building in Alcamo, Sicily, southern Italy; it is located on the ground floor of the Ex Jesuits' College.

Later (more precisely since 1866) the administration of the church passed to the Congregation of the Holy Family, which had been founded inside the Ex Jesuits' College on 15 November 1824 by Father Domenico Maria Lo Jacono, who was its director and catechist.

Next to them you can see a painting of Saint Michael (archangel), who Father Pugliese lighted candles to, in order to keep the rain away during the feast of Patrocinio, taking place on the third Sunday after Easter, when they offered lunch to poor families in piazza Ciullo.

On the side walls there are four oval paintings made by Gioacchino Speciale (1923–2004), from Partinico, realized in 1955 in substitution of the others which were in a bad state: On the ceiling there is the Ascension of Mary and of his son Jesus (by an unknown author).

At the corners of the pulpit there are two little columns adorned with Corinthian capitals which surmount two angels’ heads; behind them, on the wall, there is, as a decorative motif, a great stucco in the shape of a snail.

During the feast they place a stage in front of the Church of Jesus (chiesa del Gesù) where some poor people representing the Holy Family sit for the lunch offered and served by the members of this congregation.