She is signed to JVR Music since 2009 and released her first debut album in October of same year entitled Cindy Yen,[2] as well as her first song, "Sand Painting", a duet composed by her and sang along Jay Chou.

[7] Within eight months of signing, Yen released her debut single, "Sand Painting", a duet she composed and sang along Jay Chou.

[9] In 2010, "Sand Painting" was rated as the top ten "most popular hit songs" in China by the Mandarin Web Original Composition Pop Music Charts.

Despite the challenges of western influence in Asian musical culture, her album was musically R&B, rock, hip-hop, pop rock, hard metal and Latin hip-hop dance beats and included hits including "Stupid Fish", "Very Traveling Love", "Singing a Song Because of Longing", and "Dancing With Threat.

[16] Yen received the Best Stylistic New Artist at the Beijing MTV Super Awards in 2011,[17] and the Best Single of the Year for "Trap".

[18] On 5 July 2011, she starred as a supporting actress alongside Megan Lai and Yowei Lin in the TV series, Invaluable Treasure 1949 [zh].

[21] Since then, she has featured in First Time (2015), Sophie in Youth Power (2015), Fiona in Swimming Battle (2016), Inference Notes (推理筆記; 2017), Jenny in Memory Love (2017), Secret Lover (愛情教會我的事 – 秘密情人; 2018), Between .