Cipolletti (Spanish pronunciation: [sipoˈleti] or [tʃipoˈleti]) is a city in north of the Patagonian province of Río Negro, Argentina.

Cipolletti was founded as a fort called Confluencia by General Lorenzo Vintter, in 1881.

The name was changed later, after César Cipolletti, one of the forerunners of the study of the irrigation system of the Negro River, and heart of the apple and pear cultivation zone of the Alto Valle.

Opposite Cipolletti, across the river, lies Neuquén, capital of the province of the same name, connected to it by road and railway bridges.

Cipolletti's neighborhood of Las Perlas lies south of Neuquén, 14 km west from its city center, and has the character of an independent town.