The conference started competition at the beginning of the 2016–2017 school year following a crackdown by the IHSAA on several of the state's Catholic schools that were scheduling games against numerous teams located outside the state of Indiana.
[1] The first sporting event in the conference was a boy's varsity tennis match between Brebeuf Jesuit and Guerin Catholic that took place on August 18, 2016.
As of August 2015[update], Greg VanSlambrook is the president of the conference.
[2] Combined, the schools have accounted for 85 IHSAA state championships.
Heritage Christian will be departing for the Indiana Crossroads Conference in July of 2025.