[4] Circle of Life began her racing career in a contest for previously unraced juveniles over 1800 metres on good to firm ground at Niigata Racecourse on 28 August 2021.

[5] Circle of Life was then stepped up in class and started a 20.9/1 outsider for the Grade 3 Artemis Stakes over 1600 metres at Tokyo Racecourse on 30 October.

After being settled towards the rear of the field in the early stages by Demuro she produced a sustained run down the centre of the straight and got up in the final strides to win by a neck from Belle Cresta.

[6] On 12 December at Hanshin Racecourse, Circle of Life was promoted to the highest level to contest the Grade 1 Hanshin Juvenile Fillies over 1600 metres and went off the 4.6/1 second choice in the betting behind Namur and Sternatia in an eighteen-runner field which also included Belle Cresta, Water Navillera (winner of the Fantasy Stakes) and Namura Clair (Kokura Nisai Stakes).

She was switched to the wide outside by Demuro and produced a strong late charge, taking the lead from Water Navillera 50 metres from the finish and winning by half a length from Lovely Your Eyes.

[9] On her first appearance as a three-year-old Circle of Life started the 2.3/1 second choice in the betting for the Tulip Sho over 1600 metres at Hanshin Racecourse on 5 March.