This species is native to Puebla, Mexico, where it can be found in rocky outcrops at an elevation of 5000 feet.

[3] Cissus tiliacea has a caudiciform stem that can grow up to ten inches in diameter and yards long with additional deciduous vines that can reach lengths of five yards or longer.

During droughts, the vines die back leaving the caudex, which is normally mottled green and gray in color.

[4] This plant can tolerate high heat and full sun to light shade exposure.

[6] Frost damage occurs at 28 °F so the plant should be maintained at a temperature above this, preferably in the 40-50 °F range.