Citronelle is a city on the northern border of Mobile County, Alabama, United States.

By the time of European contact, the historic Choctaw and Creek people hunted in the area.

In the late 19th century, the town became a popular resort destination because of the climate, herbs, and healing waters.

In 1955 oil was discovered in this geologic structure at a greater depth than had previously been considered as feasible.

The discovery well yielded oil from the Glen Rose Formation at a depth of 10,879 feet (3,316 m).

[4] "Citronelle Dome is a giant salt-cored anticline in the eastern Mississippi Interior Salt Basin of southwest Alabama.

The dome forms an elliptical structural closure containing multiple opportunities for enhanced oil recovery (EOR) and saline reservoir CO2 sequestration.

Citronelle Oil Field, located on the crest of the dome, has produced more than 169 million barrels (27 million cubic metres) of 42-46° American Petroleum Institute (API) gravity oil from the Lower Cretaceous Donovan Sand.

U.S. Route 45 runs from north to south through the city, to the west of the downtown area.

[1] As of the 2020 United States census, there were 3,946 people, 1,412 households, and 1,021 families residing in the city.