CLS is orchestra-in-residence at Opera Holland Park since 2004 and holds a residency at St Paul's Cathedral.

[1] CLS performs chamber orchestra and ensemble repertoire from the Baroque period to the present day, and has a programming focus on the human voice.

In November 2009, CLS announced the appointment of Stephen Layton as its second artistic director, effective with the 2010–2011 season.

Simultaneously, CLS announced the appointment of Michael Collins also as principal conductor, effective in September 2010.

In December 2022, CLS announced the appointment of Rowan Rutter as its newest chief executive officer, effective April 2023.