Clémence Corminboeuf (born 1977) is a Swiss chemist who is Professor of Computational chemistry at the École Polytechnique Fédérale de Lausanne.

[3] After completing her doctorate, Corminboeuf was awarded a Swiss National Science Foundation fellowship to move to New York University, where she investigated the catalytic mechanisms of zinc-dependent histone deacetylases using molecular models of how the deacetylation reaction is impacted by histone-deacetylase-like proteins.

[4] She moved to the University of Georgia to work in the laboratory of Paul von Ragué Schleyer.

She serves on the executive committee of MARVEL, a Swiss National Science Foundation programme that looks to accelerate the computational design of new materials.

[2] Corminboeuf developed the Density Overlap Regions Indicator (DORI), which allows the prediction of bonding and non-covalent interactions between molecular systems.