Claire Clémence de Maillé (25 February 1628 – 16 April 1694) was a French noblewoman from the Brézé family and a niece of Cardinal Richelieu.

In love at the time with Marthe Poussard (called Mlle du Vigean),[4][5] he protested in vain against the marriage, but his father, Henri, Prince of Condé, forced him to wed Claire Clémence.

Although Claire bore her husband three children, he later claimed she committed adultery with a number of different men in order to justify locking her away at Châteauroux, but the charge was widely disbelieved: Claude de Rouvroy, duc de Saint-Simon, who admitted that she was homely and dull, however praised her virtue, piety, and gentleness in the face of relentless abuse.

[6] Upon her estranged husband's disgrace, arrest and imprisonment, in January 1650, at the fortress of Vincennes, after the Fronde, Claire Clémence distinguished herself by her energetic and devoted conduct, pursuing the struggle, raising his friends, leading them in danger and braving the king's anger, Mazarin's orders, and popular threats.

However, when a scandal arose because of her liaison with a page, the Prince exiled his wife to the Château Raoul[8] in Châteauroux, where she remained until her death in 1694.