He taught at Friendship Academy, saving up enough money go live with his brother in Kalamazoo, Michigan.
Clarence Buskirk began to study Christian Science and became a firm believer and supporter of the Church of Christ, Scientist.
He used his position on the committee to respond to claims made about Christian Science in various Indiana newspapers that he thought were incorrect or inaccurate.
Buskirk became a defender of the constitutional rights of Hoosier Christian Scientists, opposing a bill passed by the General Assembly that outlawed healing practices by anyone without a license from the State Medical Board.
In June 1903, Buskirk went to The First Church of Christ, Scientist in Boston and traveled to Concord, New Hampshire to meet Mary Baker Eddy, the founder of Christian Science.
He became a traveling lecturer, giving speeches promoting Christian Science not just in several U.S. states, but also abroad in the United Kingdom, Germany, and France.