[4] Constructed in 1909, the Clarence Moore House is an example of Beaux Arts architecture in blond Roman brick with limestone dressings; it was used by the Canadian government until the 1980s.

[6] Clarence Moore, a coal magnate from West Virginia and member of private clubs in Paris and New York City, chose the New York City-based architect Bruce Price and the Washington-based Jules Henri de Sibour to design his home in Washington, D.C.[7] At the time, Sibour was a prominent architect of large residences in Washington, including the Thomas T. Gaff House, Andrew Mellon Building, and the ambassadors' residences of Portugal, France, and Luxembourg.

In 1946, the ambassador's residence was constructed at 2825 Rock Creek Drive, and the Clarence Moore House was then used solely for embassy office space.

Clarence Moore House continued as the chancery of the Canadian Embassy until 1988, when it moved to the new and current location.

The new embassy opened in February 1993 and advocates Uzbekistan's political, commercial, and economic interests to the government of the United States.

[16] The Clarence Moore House is a classic example of the Beaux Arts architectural style and features a Louis XV-style exterior.

The 4+1⁄2-story structure includes a basement and comprises brick walls, a concrete floor, and a steel roof.

The building's north entrance on Massachusetts Avenue has a 6 x 6 foot (1.8 x 1.8 m) stoop flanked by limestone balustrades.

The flooring consists of black and white marble squares and the walls are plastered to simulate limestone.