Clarias microspilus is a species of clariid catfish from Sumatra.

It is known from short coastal rivers that drain the western face of the Leuser Mountain Range, in Aceh Province It can be found in still bodies of water around tributaries, swamps, and blackwater ponds.

The holotype was collected in Pasilembang, alongside paratypes collected from Kandang, Pucuk Lembang, Suaq Belimbing, and blackwater creeks alongside the Tapaktuan-Subulussalam road.

This species is distinguishable from all other Southeast Asian forest Clarias species (except for C. intermedius, C. insolitus, C. meladerma, C. olivaceus and C. planiceps) by the combination of the following characters:[2] It is distinguishable from C. intermedius and C. meladerma by: from C. insolitus, C. olivaceus and C. planiceps by: from C. intermedius specifically from: from C. insolitus by: and finally from C. meladerma in: Preserved specimens have been noted to be violet-gray color, slowly fading to pale-gray on ventral surfaces.

Dorsal, caudal and anal fins are also violet-gray, with a very thin margin of hyaline.