The Clarke–Glover Farmhouse is a historic house at 201 South Street in Southbridge, Massachusetts.

[1] The Clarke–Glover Farmhouse is located in a predominantly residential area west of downtown Southbridge, at the southwest corner of South and High Street, on a large level lot fringed by iron fencing.

The building corners have paneled pilasters rising to a full entablature and fully pedimented gable.

It is recessed in a paneled opening, which is framed by pilasters and topped by a peaked gable.

[2] The area where the Clarke-Glover house was built was primarily farmland until the early 19th century, when South Street began to be lined by houses of established and well-to-do families on spacious lots.