Clarke W. Brown Sr. (died May 24, 1956) was an American politician who served as the 31st Secretary of State of Michigan from 1934 to 1935 as a member of the Republican Party.

On November 13, Governor-elect Fitzgerald resigned as secretary of state.

[1] Fitzgerald had made prior arrangements with Governor William Comstock, that after Fitzgerald's resignation, Clarke W. Brown, the deputy secretary of state who had held the office for over 25 years, be appointed to fill the vacancy until the newly elected secretary of state took office on January 1, 1935.

[2] Brown was appointed by Governor Comstock, as planned, on November 15, and was sworn in to the position the same day.

[7] Brown died of a heart attack in his home in Roscommon, Michigan, on May 24, 1956.