Clarkson is a home rule-class city in Grayson County, Kentucky, United States.

[3] Clarkson is known for its Honeyfest and is home to The Walter T. Kelley Company, a manufacturer of beekeeping equipment.

Clarkson is located directly east of Leitchfield along U.S. Route 62 and the Western Kentucky Parkway.

32.6% of all households were made up of individuals, and 12.7% had someone living alone who was 65 years of age or older.

In 1926, Pauline Bell of Clarkson won the 2nd Scripps National Spelling Bee.