Gensac is the oldest nominee to date in the category César Award for Best Supporting Actress, nominated in 2015 for her role as Marthe in the film Lulu femme nue.

In 1952, Gensac portrayed the character of Evelyne in her first feature film, La Vie d'un homme honnête.

[1] She collaborated on a number of films with Louis de Funès, often playing his wife, to international acclaim.

After De Funès's death in 1983, Gensac was rarely involved in film, but was active as a theater actress.

[4] Claude Gensac was married twice: from 1952 to 1954 with the actor Pierre Mondy and from 1958 to 1977 with Henri Chemin, a racer and PR Manager of Ford France with whom she had a son.