Claysville is an unincorporated community in Boone County, in the U.S. state of Missouri.
[1] It is the southernmost settlement in Boone County.
Claysville was laid out in 1844, and named after Henry Clay, the Kentucky statesman.
[2] A post office called Claysville was established in 1850, and remained in operation until 1908.
This Boone County, Missouri state location article is a stub.