Claysville is a borough in Washington County, Pennsylvania, United States and part of the Pittsburgh metropolitan area since 1950.

The Montgomery House was listed on the National Register of Historic Places in 2002.

There were 261 housing units at an average density of 847.1 per square mile (327.1/km2).

The racial makeup of the borough was 99.45% White, 0.28% African American, and 0.28% from two or more races.

19.4% of all households were made up of individuals, and 14.0% had someone living alone who was 65 years of age or older.