Clifton is a town in St. Lawrence County, New York, United States.

The Town of Clifton is in the southern part of the county, within the Adirondack Park.

The first town meeting was held in the office of the Clifton Iron Mine.

Part of the southern town line is the border of Hamilton and Herkimer counties.

New York State Route 3 crosses the town as a major east–west highway.