Clinofibrate

Clinofibrate (INN) (trade name Lipoclin) is a fibrate and a derivative of Bisphenol Z.

[1] The reaction between cyclohexanone and phenol gives Bisphenol Z (3).

[2] This is treated with chloroform and methyl ethyl ketone in the presence of base.

The resulting Bargellini reaction gives clinofibrate.

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