Evidence of the presence of the Cualann Celtic people (an early tribe possibly the Cauci on Ptolemy's world map) can be found in various mounds and raths.

[3] Clondalkin is believed to have been founded by Saint Cronan Mochua as a monastic settlement on the River Camac over 1,400 years ago (possibly late 6th or early 7th centuries).

One of the early Norse kings of Dublin, Amlaíb Conung, built a fortress on the site in the middle of the 9th century.

In 867 a force led by Cennétig mac Gaíthéne, king of Loígis, burned the fortress at Clondalkin and killed 100 of Amlaíb's followers.

[8] The district remained under Norse control until the Viking defeat by Brian Boru at the famous Battle of Clontarf in 1014.

Clondalkin witnessed another historic event during the Norman invasion in 1171 with a battle there between Richard de Clare (Strongbow) and the last High King of Ireland Ruaidhrí Ua Conchabhair.

An exclave of the parish, consisting of the single townland of Blundelstown, is located in the neighbouring barony of Newcastle to the west.

Centuries later, Clondalkin was the scene for some fighting in the 1641 Rebellion, when the Gaelic Irish in Ulster, and later in the rest of the kingdom, and the Old English in the Pale of Leinster rebelled against rule from Westminster.

[citation needed] The village centre also has several small businesses including solicitors, restaurants, pubs, hairdressers and pharmacies.

[16] North Clondalkin Library, opposite the Immaculate Heart of Saint Mary's Church, was due to open in late 2019.

[citation needed] Microsoft, Google, Amazon, Arytza, Wyeth, Takeda and Pfizer all have significant data centres and development facilities in the Grange Castle Business Park.

Farmers from Belize and El Salvador, along with local councillors and community representatives, attended a ceremony in Clonburris National School to mark the occasion.

[17] Clondalkin is served by public transport to Dublin city centre, to nearby suburbs, and to neighbouring settled areas such as Tallaght.

[20] The original Clondalkin station was demolished in 2008 to facilitate a four-line track, allowing express trains to pass through without affecting local services on the Kildare line.

Bus Éireann services stop to collect and set down passengers at Newlands Cross, on the N7 road near Clondalkin.

Club members have represented Dublin in the inter-county competition since the nineteenth century, when Tom Errity won several All-Ireland Senior Football medals in the 1890s.

More recently, Jim Gavin won an All-Ireland senior medal with Dublin in 1995 and several as a manager in the 2010s.

[citation needed] Bernard Dunne the former WBA Super Bantamweight World Champion is from Neilstown in Clondalkin.

Kenny Egan, winner of a silver medal for boxing in the 2008 Olympics, comes from Clondalkin, originally Woodford estate.

[citation needed] The National Baseball Facility in Ireland, O'Malley Field, is located in Corkagh Demesne Park, in southwest Clondalkin.

[citation needed] The grassroots Irish language project Pop-Up Gaeltacht was co-founded by Clondalkin native Peadar Ó Caomhánaigh.