CloudFront has servers located in the United Kingdom, Ireland, the Netherlands, Germany, Spain, Hong Kong, Singapore, Japan, Taiwan, Vietnam, Indonesia, India, Australia, South America, Africa, and several major cities in the United States.

In November 2022, the service operated from 400 edge locations on six continents.

CloudFront competes with larger CDNs, such as Akamai, Azion, Cloudflare, and Edgio (previously known as Limelight Networks).

Upon launch, Larry Dignan of ZDNet News stated that CloudFront could cause price and margin reductions for competing CDNs.

If enabled, the logs are stored on Amazon S3 buckets which can then be analyzed.