[2] On March 1, 2018, Marymount and Wesley departed the CAC for the newly-formed Atlantic East Conference (AEC) following the end the 2017-18 academic year.

[6] On December 11, 2019, Southern Virginia departed the C2C to join the USA South Athletic Conference, effective after the 2020-21 academic year.

[12] On March 17, 2021, Mills announced that it would end conferment degrees to become a research institution after the 2022-23 school year, thus dissolving their athletic programs.

[13][14][15] On August 4, 2021, St. Mary's rejoined the C2C as an associate member in men's and women's indoor and outdoor track & field.

[16] On January 11, 2022, the University of Wisconsin–Platteville joined the C2C as an associate member for men's soccer, starting in the 2022 fall season (2022–23 academic year).