Colegio Ponceño is a Roman Catholic, Piarist, pre K-12 preparatory school located in Ponce, Puerto Rico.

It is now located in Barrio Coto Laurel in Ponce, where it boasts one of the largest campuses and most modern school facilities in the Island.

Colegio Ponceño is accredited by the Puerto Rico Department of Education and by the Middle States Association of Colleges and Schools.

[citation needed] Since its establishment, the school has upheld high Catholic pedagogical standards and excelled in preparing students for higher education, both in Puerto Rico and the United States mainland.

In every graduating senior class, Colegio Ponceño has consistently produced students who have gone on to become successful professionals in the fields of medicine, law, engineering, and business, among others.