The parent school was founded in 1750 by M. Paula de la Santisima Trinidad, a Dominican Tertiary from Spain.

In 1801, the chairmanship of its Board of Control was given by the Spanish governor to the Vicar Provincial of the Order of Recollect Fathers in the Philippines, and his successors, and it has remained with them up this day.

Rosa continued to give Christian formation to young Filipino girls until World War II, when in the battle of Manila, between the Japanese and American forces, its school buildings were totally destroyed.

In 1964, these Sisters, animated with the same sentiment that inspired M.Paula when she founded the school in Intramuros, responded to the demands for a Catholic institution in the then growing municipality of Makati.

Colegio de Sta Rosa continued to prosper and gain a reputation as a quality school.

The Servants of Saint Joseph, desiring to return to the original charism of their Congregation, withdrew from administering Colegio de Sta.