He was the eldest son of Archibald Campbell, 4th Earl of Argyll and his second wife Margaret Graham.
Some "women and men suspected of witchcraft and sorcery were apprehended" and kept in prison or released on caution, until further trial.
Argyll also ensured churches had ministers or readers teaching the Bible in Scottish Gaelic as translated by the late John Carswell, Bishop of the Isles.
He sought the resolution of feuds between Aonghus MacDonald of Kintyre and Lachlan Mor Maclean, and MacConnell Gorm, Lord of the Isles, and the Laird of Glengarry.
[1] In May 1583, James VI granted Colin Argyll and his wife Annas or Agnes Keith the lands of Lundie, Forfarshire.