[3][4][5] The New York Yankees selected Curtis in the fourth round of the 2006 Major League Baseball Draft.

[14] On June 22, Curtis recorded his first major league hit, a double off of Chad Qualls of the Arizona Diamondbacks.

He was pinch hitting for Brett Gardner, who was ejected while batting with an 0–2 count in the bottom of the seventh inning.

[24] Curtis signed with the Somerset Patriots of the independent Atlantic League of Professional Baseball a few days after he was released by the Yankees.

The treatment involved surgery to remove the tumor and parts of the affected veins and regular blood tests.

While battling the disease, fellow testicular cancer survivor Lance Armstrong gave him an autographed book.