Myler started his career working for the Catholic Pictorial in Liverpool,[2] before joining West Lancs Press Agency in Southport The Sun and later the Daily Mail.
He returned to the Sunday Mirror in 1998, but resigned in 2001 after Judge David Poole ruled that an article he had published regarding accusations of assault against Leeds United F.C.
[6] Shortly after, Myler moved to the United States and was appointed executive editor of the New York Post.
[6] He returned to London in 2007 to become editor of the News of the World[1] and remained in post until the paper ceased publication on 10 July 2011.
[10] In January 2012, Myler was appointed editor-in-chief of the New York City Daily News.