Mahatma Jyotiba Phule, the noted thinker, social reformer and agriculturist of Pune appealed, persuaded and convinced the British Government to set up institutions for agricultural education and research in India.

The main building with its grand dome and entrance hall for teaching and research in Agriculture, Botany, Mycology and Economics was ready in 1911 and was inaugurated by Lord Sydenham, the Governor of Bombay.

It was here that the Mahatma Phule Krishi Vidyapeeth was formed, which was later shifted to Rahuri.

The Bombay University in the year 1909 further extended the scope of these studies, raised the standards and instituted the degree of Bachelor of Agriculture (B.Ag.).

In 1969, the college was transferred to the Mahatma Phule Krishi Vidyapeeth, Rahuri established in that year.