Originally founded on Chacarilla Street in the Guadalupe neighbourhood on November 14, 1840,[2] it moved in 1909 to its current location on Alfonso Ugarte Avenue, built during the government of Augusto B.

[5] In 1839, during the second government of President Agustín Gamarra, there were already numerous state and private educational establishments in Lima aimed at careers as lawyers, priests or doctors, so a preparatory or elementary school was necessary.

Driven by this motivation, landowner Domingo Elías and the wealthy Spaniard Nicolás Rodrigo, in a notice published on November 14, 1840, announced that they had decided to open the school for the next year, placing it under the immediate direction of a priest.

Lorente's presence meant the elevation of the quality of teaching, making the Guadalupe school a center for upper secondary education and, furthermore, the ideological antagonist of the San Carlos Convictory, a bastion of conservatism, whose rector was the famous religious Bartolomé Herrera [es].

Shortly after, it was reopened as a private institute, with authorization from the Council, but the government of Francisco García Calderón once again granted it national status.

Once the war ended and the Chilean troops were repatriated, the school was another example of the vandalism and pillage unleashed by the invaders on Peruvian soil: laboratories, cabinets, natural history museum and library had disappeared or were in rubble; even the floors and doors were missing.

Given the shortage of resources, the possibility of closing the school was considered, which was avoided by the dismissal of the teaching staff, who had already carried out their work without pay during the Chilean occupation.

[11] From 1886 to 1899, Sebastián Lorente Benel [es] (son of the teacher and historian of the same name) served as its director, who was responsible for restoring the institutional life of the school to its normality, despite the economic hardship.

The Haussmann commission, from France, recommended its new location on the current Alfonso Ugarte Avenue, with the school forming part of a boulevard with the Loayza Hospital, Bartolomé Herrera, Plaza Dos de Mayo, etc.

They were in charge of importing the most modern educational cabinets of the time (museums of Economics, Natural Sciences, Electricity, Physics, Chemistry, etc).

The chapel represents over time the Catholic faith of all the students and teachers who, by tradition, accompany in a mass and procession, during the eve of the institution's anniversary, normally held on November 13 of each year (or occasionally, on previous days).

The best students from those annexes and from the national schools in the provinces were selected to study at the central location on Alfonso Ugarte Avenue.

The familiar school attire that was known as “Commando” was created as an alternative to solve the economy of parents, due to its variety of use and its durability.

Mr. Alfredo Maccera, manager of the textile manufacturing division of the “Reiser & Curioni” house, began to sketch a design that would meet the most required conditions to dress school youth and, above all, at a low cost.

Maccera and Gonzáles Iglesias had several conversations and, after studying the pros and cons, the first “Comando” model emerged, designed exclusively for the Guadalupe school.

The Minister of Education at the time, General Juan Mendoza, took interest in the Guadalupe experience, which is why he recommended, starting in 1949, according to a supreme resolution, the use of the new uniform in national and private establishments.

They headed to the nearby American Embassy to express their rejection of a law that violated the sovereignty of the two hundred miles, as stated on a flyer on that occasion.

In June it was reported that there would be an increase in fares, in which case the night school's students marched to the premises of "El Comercio" and "la Prensa" to express their formal rejection.

[15] Under the military government of Juan Velasco Alvarado, the boarding school regime ceased to exist,[15] the offices that formulated and managed the Educational Reform of 1973 were installed on the second floor and due to the high demand for student admission, the afternoon and morning system changed to a two-shift regime: one in the morning, one in the afternoon, being able to meet the student request of the time.

A stadium, known as the Estadio Guadalupano, is located in the district of San Martín de Porres, also in Lima, it is intended for physical culture and the practice of sports.

In 1940, commemorating the first centennial of the school's foundation, the various classes met in the Campus Assembly Hall and under the presidency of Melitón Porras Osores [es], the various commissions that would shape the new institution were named.

This mansion witnessed great civic-cultural and patriotic events attended by ministers of states, as well as presidents of the Republic, such as Dr. Manuel Prado y Ugarteche and the architect Fernando Belaúnde Terry.