[1][2][3][4] Colo was born at the Columbus Zoo and Aquarium to Millie Christina (mother) and Baron Macombo (father), and lived there for her entire life.

Colo and Bongo had three offspring; Emmy on February 1, 1968, Oscar on July 18, 1969, and Toni on December 28, 1971.

[9] Although Colo did not raise any of her own offspring, she reared her twin grandsons, Macombo II and Mosuba, from birth.

[10] Colo also acted as a guardian for her grandson, named J.J. after "Jungle" Jack Hanna with whom he shares a birthday.

[12] Colo became the oldest living gorilla in captivity following the death of 55-year-old Jenny in September 2008.