By the mid-1850s, the Island Colony's non-indigenous population was around 800 people; a mix of mostly British, French-Canadian, Hawaiians, but with handfuls of Iroquoians, Métis and Cree in the employ of the fur company, and a few Belgian and French Oblate priests.

[2] Three years earlier, the Oregon Treaty had established the boundary between British North America and the United States west of the Rocky Mountains along the 49th parallel.

All this changed with the Fraser Canyon Gold Rush of 1857–1858, when the non-aboriginal population of the mainland swelled from about 150 Hudson's Bay Company employees and their families to about 20,000 prospectors, speculators, land agents, and merchants.

Douglas continued to administer the mainland colony in absentia from Victoria, but Sir Arthur Kennedy was appointed to succeed him as Governor of Vancouver Island.

Major players in the Confederation League such as Amor De Cosmos, Robert Beaven, and John Robson pushed for union primarily as a way of advancing both the economic health of the region, as well as increased democratic reform through truly representative and responsible government.

Seymour, ill and beset by protests that he was dragging in his feet in completing negotiations for the HBC's territory, was facing the end of his term, and Macdonald was pressing London to replace him with Sir Anthony Musgrave, outgoing governor of the Colony of Newfoundland.