The district developed between about 1880 and 1944 and includes examples of a variety of popular architecture styles.

Located in the district is the separately listed Tyrrell County Courthouse.

Other notable buildings include Snell's Inn (c. 1910), Columbia Garage (c. 1930), Columbia Christian Church (c. 1905), McClees-Coffield House (c. 1880), Combs-Hussey House (c. 1900), Frederick L. W. Cohoon House (c. 1904), Columbia Baptist Church (1905), W. J.

White Building (1931-1932), Columbian Theatre (c. 1935), Wesley United Methodist Church (1912), St. Andrews Episcopal Church (1909), Tyrrell County Jail (c. 1910), Merchants and Farmers Bank / East Carolina Bank (c. 1905), Tyrrell County Bank (c. 1930), and Columbia Theatre (c.

This article about a property in Tyrrell County, North Carolina on the National Register of Historic Places is a stub.