The Columbia Memorial Space Center (CMSC) is a science museum in the Los Angeles area, in City of Downey, California, US.

[2] The center's stated mission is to "ignite people's passion in science, technology, engineering, and space while honoring Downey's aerospace history.

[4][5] On November 7, 2008, a propane tank exploded during the filming of an episode of the television series Bones, causing an electrical fire, without damage to the museum.

[6] Designated a Challenger Learning Center,[7] the museum has a variety of camps, workshops, and other monthly events to generate interest in STEM, and hands-on exhibits.

[2] In 2012, the first "Space Shuttle" – a wood and plastic full-scale mockup built by North American Rockwell in 1972 – was placed on temporary display at the center.