It occurs in Ohio, Pennsylvania, and Virginia in the United States, and in Ontario, Canada.

[2] Its members include: Bellepoint, Marblehead, Tioga Ash Bed, Venice, Delhi, Klondike, and East Liberty.

The Columbus Limestone contains brachiopods, trilobites, bryozoans, mollusks, corals, stromatoporoids and echinoderms (including crinoids).

Due to their mid-continent depositional environment, the fossils are almost free of deformation caused by tectonic activity common in the Appalachian Mountains.

Relative age dating of the Columbus Limestone places it in the Early to Middle Devonian period.